Eczema (also called atopic dermatitis, or AD) is a common skin condition that causes itching, discoloration, inflammation, and roughened patches of skin. AD is common worldwide. About 31 million Americans are diagnosed with the condition.
Although eczema is a common condition, some people seem to be more at risk for developing severe eczema than others. Race and ethnicity are two factors that have been studied for their impact on eczema severity.
Researchers have found several associations between ethnicity and eczema, including:
People with darker skin are also more likely to be diagnosed later in life than those with lighter skin. This could be due in part to the fact that doctors are more likely to be taught how to recognize eczema on lighter skin (often a reddened rash) as opposed to darker skin (often having a gray or violet appearance). It’s worth noting that among all medical specialties, dermatology is the second least diverse in terms of doctors. Dermatology training programs are trying to correct the disparity and focus teaching on learning more about different skin tones.
Black people can also have eczema symptoms that are less common among white people — for example, small bumps on the skin or around hair follicles. This symptom could be caused by papular eczema or follicular accentuation.
Research suggests a link between certain genes and eczema — such as those affecting the skin protein filaggrin and others that affect immune regulation. But the filaggrin gene mutation is relatively rare in Asian and Black populations. There is some evidence that Black skin produces fewer ceramides, another molecule that contributes to the skin barrier. More research is needed to fully understand possible genetic links between eczema and race.
The search for answers is complicated by the fact that African American and Latino populations are underrepresented in genetic research as a whole. While these populations comprise approximately 30 percent of the American population, genetic data representing Black people comprises only 2 percent of research. Data for Hispanic people reflects only 0.5 percent. The result is that for most diseases, there is not enough data to draw strong conclusions about how genetic factors affect disease.
In general, some factors that affect the severity of eczema symptoms include:
Studies have shown that African American children are more likely to be exposed to these known risk factors. Evidence suggests that these environmental factors may play a role in explaining why African Americans are more likely to develop eczema — and to experience more severe symptoms.
Greater exposure to polluted environments — which can directly lead to higher rates of disease, including eczema — is an example of structural, or institutionalized, racism. Structural racism negatively affects the health of communities of color in measurable ways. For example, the fact that Black people in America have shorter life expectancies than white people is a measurable health disparity. Some aspects of structural racism that affect health outcomes can be attributed to the redlining system, which cut off minority communities from investment for decades.
Despite the fact that Black people are more likely to be diagnosed with advanced AD, studies show that they are also less likely to be receiving treatment for eczema than other racial and ethnic groups. This may explain in part why Black people experience more severe disease when compared to white people. Black people are less likely to access primary health care, less likely to have health insurance, and more likely to have lower socioeconomic status compared with other groups.
Black Americans experience eczema at higher rates and with more severe symptoms than other groups, but there has not been enough research to fully explain why.
One area that requires more research is the effectiveness of eczema treatments among different racial and ethnic groups. Currently, we don’t know whether more severe disease may develop because eczema treatments don’t work as well for some people compared with others.
Also, the majority of medical research has historically focused on white people. More research needs to be done to understand and address the multiple disparities in the way eczema affects people of different races and ethnicities.
Efforts are underway to increase representation in studies on allergic and immunologic diseases, which include atopic dermatitis. Hopefully the future will bring a more comprehensive understanding of the ways in which race, ethnicity, genes, and environmental factors influence eczema — and greater access to timely treatment for all people.
MyEczemaTeam is the social network for people with eczema and their loved ones. On MyEczemaTeam, more than 41,100 members come together to ask questions, give advice, and share their stories with others who understand life with eczema.
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